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          李闖創課題組完成高難度明星分子Vinigrol的最短全合成 近日,我?;瘜W系教授李闖創課題組在國際頂尖化學期刊《美國化學會志》(Journal of the American Chemical Society,簡稱JACS)發表論文,報道了明星天然產物Vinigrol的高效不對稱全合成。
          權澤衛課題組在《先進材料》發表重要研究進展 近日,南科大化學系教授權澤衛課題組在新型納米金屬間化合物領域取得最新進展,該成果發表在材料領域頂級期刊《先進材料》(Advanced Materials,IF:25.806)。
          化學系徐晶課題組在《美國化學會志》發表成重要進展 近日,徐晶課題組再次在復雜籠狀天然產物全合成領域取得重要進展,在《美國化學會志》發表重要研究論文,報道復雜籠狀虎皮楠生物堿Caldaphnidine O的國際首次全合成。
          化學系徐晶課題組在《美國化學會志》發表成果 近日,我?;瘜W系副教授徐晶課題組成功地完成了復雜虎皮楠生物堿Dapholdhamine B及其內酯衍生物的對映選擇性全合成工作,相關研究成果在《美國化學會志》(J. Am. Chem. Soc.)上發表。
          化學系劉心元課題組在自由基不對稱化學領域取得重要研究進展 近日,我?;瘜W系教授劉心元課題組在不對稱碳–碳鍵偶聯領域取得了重要研究進展。研究成果近期在《自然化學》(Nature Chemistry,IF:23.193)在線發表。
          化學系黃文忠課題組在《美國化學會志》發表最新研究成果 近日,我?;瘜W系副教授黃文忠課題組成功合成了一系列高發光強度的銠(III)配合物,并首次將其應用于有機電致發光二極管,取得重要研究進展。該成果在國際頂尖化學期刊《美國化學會志》
          化學系優秀畢業生
          優秀畢業生

          何振宇

          副教授

          化學系

          0755-88018318

          jasonhcy@sustech.edu.cn

          研究方向
          金屬有機催化應用研究
          Dr. Chun-Yu Ho received his Ph.D. in 2005 under the supervision of Prof. Dan Yang in The University of Hong Kong for organocatalytic asymmetric epoxidation. After pursing post-doctoral research during 2005-07 with Prof. Timothy F. Jamison in MIT for transition metal catalysis, he started his independent career at The Chinese University of Hong Kong (CUHK) as a Research Assistant Professor at the end of 2007. Now he is Associate Professor in Southern University of Science and Technology in 2013 and Honorary AP of CUHK. He is the recipient of The Croucher Foundation Fellowship of Hong Kong, Asian Core Program Lectureship Award from both Japan in 2010 and Singapore in 2011, recognized as Overseas High-Caliber Personnel from Shenzhen in 2013, and awarded ACS Excellence in Science Symposium: The Journal of Organic Chemistry and Organic Letters Best Poster in 2013.
          2005-07 The Croucher Foundation Fellowship Award
          2010-11 The Asian Core Program Lectureship Award (from Japan)
          2011-12 The Asian Core Program Lectureship Award (from Singapore)
          2012 Publication honored in RSC Chem. Commun. 2012 Emerging Investigator Issue
          2012 One of the three invited oversea lecturers in 3rd Symposium of Molecular Activation
          Directed toward Straightforward Synthesis, at Hanamaki, Iwate (MEXT, Japan)
          2012 Adjunct AP at Southern University of Science and Technology
          2013 Adjunct AP at The Chinese University of Hong Kong
          2013 Editorial Member of Natural Products Chemistry & Research Journal
          2013 Recognized as Overseas High-Caliber Personnel (Peacock Program Awardee from
          Shenzhen Government) 深圳市孔雀計劃 B 類人員
          2013 Presentation in ISORM, a Celebration in Honor of Grubbs, Houk, Schleyer & Truhlar
          2013 ACS Excellence in Science Symposium: The Journal of Organic Chemistry and Organic
          Letters Best Poster Award
          2014 Invited Contribution in Synlett Special Issue:
          Catalysis with Sustainable Metals (1 of 18 papers)
          2014 Invited Contribution in J. Org. Chem. Special Issue:
          Mechanisms in Metal-Based Organic Chemistry (1 of 37 papers from 14 countries)
          2015 Paper recognized as very important paper in the area of N-Heterocyclic Carbene (VIP)
          and Front Cover Story in Angew. Chem. Int. Ed.
          Develop novel, practical, green and energy efficient methods for:
          1. Organic chemical library synthesis;
          2. Sustainable organic/hybrid materials preparations and applications;
          3. Phosphonylation and cyanation to access important biological compounds and their
          subsequent SAR studies.
          A/ US Non-Provisional Patent granted or filed (As the sole inventor):
          1. Ho, C.-Y. US8354554B2 “Process for Preparing Organometalloids”
          2. Ho, C.-Y. US8383873B2 “Terminal 1,1-Disubstituted Olefin, Methods of Making & Using
          Thereof”
          3. Ho, C.-Y. US regular patent filed, application number: 13/415304, title remains confidential
          4. Ho, C.-Y. PCT filed, application number: PCT/CN2014/082861, “Process for Preparing
          Branched Allyl Compounds”
          5. Ho, C.-Y. PCT filed, application number: PCT/CN2015/071187, title remains confidential
          B/ Invited Review (As corresponding author):
          1. “NHC-Ni-H Reactions with Simple Olefins: Advances in Hydroalkenylation, Polymerization, and
          Ionic Liquid Synthesis.”
          Ho, C.-Y.*; He, L.; Chan, C.-W. Synlett 2011, SynPacts issue, 1649.
          2. “Catalytic Addition of Simple Alkenes to Carbonyl Compounds Using Group 10 Metals”
          Ho, C.-Y.*; Schleicher, K. D.; Chan, C.-W.; Jamison, T. F.* Synlett 2009, 2565.
          C/ Book Chapter:
          1. “NHC-Ni Hydride Catalyzed Terminal Disubstituted Alkene Synthesis”
          Ho, C.-Y.*; He, L. ISBN 978-3-8465-0051-4, 88pgs.
          2. “Introduction to General, Organic and Biological Chemistry” Global Edition
          D/ Paper (Since 2005):
          a/ Catalysis having C-C Bond Formation
          1. “Catalytic Asymmetric Hydroalkenylation of Vinylarenes: Electronic Effects of Substrates and
          Chiral N-Heterocyclic Carbene Ligands”
          Ho, C.-Y.*; Chan, C.-W.; He, L. Angew. Chem. Int. Ed. 2015, 54, 4512.
          Highlighted thrice:
          Featured as Front Cover & VIP (Very Important Paper),
          in Angew. Chem. Int. Ed. 2015, 54 (15), 4403.
          in ChemCatChem 2015, 7, 1639 by Prof. Gerhard Hilt &
          in X-Mol on 2015-04-17
          2. “Substituted 1,3-cyclohexadiene synthesis by NHC-Nickel(0) catalyzed [2+2+2] cycloaddition of
          1,n-Enyne”
          Zhao, J.-P.; Chan, S.-C.; Ho, C.-Y.* Tetrahedron 2015, 71, 4426.
          Invited Special Symposium-in-Print: Progress in organic synthesis: New reactions,
          strategies and targets.
          3. “Medium-Sized Heterocycle Synthesis by the Use of Synergistic Effects of Ni-NHC and γ
          Coordination in Cycloisomerization.”
          Ho, C.-Y.*; He, L. J. Org. Chem. 2014, 79, 11873.
          Invited Special Issue:
          (1 of 37 from over 14 countries)
          Highlighted twice:
          SynFacts 2014, 10, 913 (by Prof. V. Snieckus)
          Organic Chemistry Highlights, 2015, (by Prof. D. F. Taber)
          “C-O Ring Construction”.
          4. “Nitrate-Enhanced NHC-NiH Catalyzed Tail-to-Tail Vinyl Ether Dimerization.”
          He, L.; Ho, C.-Y.* Synlett 2014, 25, 2738.
          Invited Special Issue: Catalysis with Sustainable Metals. (1 of 18 papers)
          5. “Shuffle off the Classic β-Si Elimination by Ni-NHC Cooperation:
          Implication for C-C Forming Reactions Involving Ni-Alkyl-β-Silanes.”
          Ho, C.-Y.*; He, L. Chem. Commun. 2012, 48, 1481.
          Honored in Emerging Investigator Issue (1 of 71 papers in the year)
          Has been recommended on PubMed advanced by Novo Nordisk®
          6. “Catalytic Intermolecular Tail-to-Tail Hydroalkenylation of Styrenes with alpha Olefins:
          Regioselective Migratory Insertion Controlled by a Nickel/N-Heterocyclic Carbene.”
          Ho, C.-Y.*; He, L. Angew. Chem. Int. Ed. 2010, 49, 9182.
          Highlighted thrice:
          SynForm 2011, issue 2, A15-16 & as Cover (by Prof. M. Zanda);
          SynFacts 2011, issue 3, 310 (by Prof. P. Knochel);
          Organic Chemistry Highlights, 2011 (by Prof. D. F. Taber)
          “Functionalization & Homologation of Alkenes”.
          7. “Cyanative Alkene-Aldehyde Coupling: Ni(0)-NHC-Et2AlCN Mediated Chromanols Synthesis with High cis-Selectivity at room temperature.” Ho, C.-Y.* Chem. Commun. 2010, 46, 466.
          8. “Nitrile assisted, Bronsted acid catalyzed regio and stereoselective diarylphosphonylation of allyl silyl ethers.”
          Ho, C.-Y.*; Chan, C.-W.; Wo, S.-K.; Zuo, Z.; Chan, L.-Y. Org. Biomol. Chem. 2010, 8, 3480.
          9. “Alpha Olefins as Alkenylmetal Equivalents in Catalytic Conjugate Addition Reactions.”
          Ho, C.-Y.; Ohmiya, H.; Jamison, T. F.* Angew. Chem. Int. Ed. 2008, 47, 1893.
          10. “Highly Selective Coupling of Alkenes and Aldehydes Catalyzed by NHC–Ni–P(OPh)3: Synergy
          Between a Strong σ-Donor and a Strong π-Acceptor.”( Hot Paper)
          Ho, C.-Y.; Jamison, T. F.* Angew. Chem. Int. Ed. 2007, 46, 782.
          11. “Nickel-Catalyzed Coupling of Alkenes, Aldehydes, and Silyl Triflates.”
          Ng, S.-S.; Ho, C.-Y.; Jamison, T. F.* J. Am. Chem. Soc. 2006, 128, 11513.
          12. “Nickel-Catalyzed, Carbonyl-Ene-Type Reactions: Selective for Alpha Olefins and More Efficient
          with Electron-Rich Aldehydes.”
          Ho, C.-Y.; Ng, S.-S.; Jamison, T. F.* J. Am. Chem. Soc. 2006, 128, 5326.
          b/ Catalysis having C-Heteroatom Bond Formation
          1. “Highly Chemoselective Reductive Amination of Carbonyl Compounds Promoted by
          InCl3/Et3SiH/MeOH System.”
          Lee, O.-Y.; Law, K.-L.; Ho, C.-Y.; Yang, D.* J. Org. Chem. 2008, 73, 8829.
          2. “Fluorinated Chiral Secondary Amines as Catalysts for Epoxidation of Olefins with Oxone.”
          Ho, C.-Y.; Chen, Y.-C.; Wong, M.-K.; Yang, D.* J. Org. Chem. 2005, 70, 898.
          c/ Collaborative Pharmaceutical Research Papers Published:
          1. "Synthesis, biological activity, and biopharmaceutical characterization of tacrine dimers as
          acetylcholinesterase inhibitors."
          Qian, S.; He, L.; Mak, M.; Han, Y.; Ho, C.-Y.*; Zuo, Z.* Int. J. Pharmaceutics, 2014, 477, 442.
          2. "In Vitro Anti-acetylcholinesterase Activities and Permeabilities of Novel Potential Anti-Alzheimer's Agents".
          Qian, S.; Mak, M.; He, L.; Ho, C.-Y.*; Han, Y.*; Zuo, Z.*
          Paper presented in the 9th International ISSX Meeting, organized by International Society for the Study of Xenobiotics, 1 pgs. Istanbul, Turkey, 2010.09.04.
          3. "Structure-activity and structure-permeability relationships of novel anti-Alzheimer’s agents tacrine dimers".
          Qian, S.; He, L.; Mak, M.; Ho, C.-Y.*; Han, Y.*; Zuo, Z.* Paper presented in the 2011 AAPS Annual Meeting and Exposition, organized by The American Association of Pharmaceutical Scientists, 1 pgs. Washington, DC, USA, 2011.10.26.
          4. "Development of LC/MS/MS method for determination of a novel tacrine dimer HLS-3 in rat plasma and its application to pharmacokinetic study".
          Qian, S.; He, L.; Wo, S-K.; Mak, M.; Han, Y.*; Ho, C-Y.*; Zuo, Z.* Paper presented in the 2012 AAPS Annual Meeting and Exposition, organized by The American Association of Pharmaceutical Scientists, USA, 2012.10.14.

          Professional Services:
          * Serve as reviewer of the following journals:
          Angewandte Chemie International Edition
          Chemistry An Asian Journal
          Chemistry An European Journal
          Journal of the American Chemical Society (JACS)
          Journal of Organometallic Chemistry
          Organic Letters
          Organic and Biomolecular Chemistry
          RSC Advance
          Synthesis
          Synlett
          * Serve as an Editorial member of the Journal below:
          Natural Products Chemistry & Research Journal

          Graduate Students Training
          Awards the Trained Graduate Students Received in our Group:
          * 1 Asian Core Program (ACP), Junior Workshop on Cutting-Edge Organic Chemistry in Asia Poster Award (2010).
          * 1 Hong Kong Graduate Symposium Poster Award (Organic Chemistry Section).
          Awarded by Hong Kong Graduate Symposium Committee (2011)
          * 1 Hong Kong PhD Fellowship. Awarded by UGC (2011)
          * 1 Student awarded Madam Wong Siew Khoon Scholarship, nominated by the Science Faculty Scholarship Committee as CUHK representative (2012).
          * 1 Student awarded Faculty of Science Postgraduate Student Research Output Award (2012, one Award in each year).
          Professional Services:
          * Serve as reviewer of the following journals:
          Angewandte Chemie International Edition
          Chemistry An Asian Journal
          Chemistry An European Journal
          Journal of the American Chemical Society (JACS)
          Journal of Organometallic Chemistry
          Organic Letters
          Organic and Biomolecular Chemistry
          RSC Advance
          Synthesis
          Synlett
          * Serve as an Editorial member of the Journal below:
          Natural Products Chemistry & Research Journal

          Graduate Students Training
          Awards the Trained Graduate Students Received in our Group:
          * 1 Asian Core Program (ACP), Junior Workshop on Cutting-Edge Organic Chemistry in Asia Poster Award (2010).
          * 1 Hong Kong Graduate Symposium Poster Award (Organic Chemistry Section).
          Awarded by Hong Kong Graduate Symposium Committee (2011)
          * 1 Hong Kong PhD Fellowship. Awarded by UGC (2011)
          * 1 Student awarded Madam Wong Siew Khoon Scholarship, nominated by the Science Faculty Scholarship Committee as CUHK representative (2012).
          * 1 Student awarded Faculty of Science Postgraduate Student Research Output Award (2012, one Award in each year).
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